A micro electronic pill is basically a multi channel sensor used for remote bio medical measurements using microtechnology this has been developed for the internal study and detection of diseases and abnormalities in the gastro intestinal GI tract where restricted access prevents the use of traditional endoscopy the measurement parameters for detection include real time remote recording of temperature, pH, conductivity and dissolved oxygen in the GI tract This paper with the design of the micro electronic pill which mainly consists of an outer biocompatible capsule encasing 4 channel micro sensors a control chip, a discrete component radio transmitter and 2 silver oxide cells. We have therefore described about the multichannel sensor, which has been implemented in remote biomedical using micro technology, the micro electronic pills, which is designed to perform real time measurements in the GI tract providing the best in vitro wireless transmitter, multi channel recordings of analytical parameters. The invention of transistor enabled the first use of radiometry capsules, which used simple circuits for the internal study of the gastro-intestinal (GI)  tract. They couldn’t be used as they could transmit only from a single channel and also due to the size of the components. They also suffered from poor reliability, low sensitivity and short lifetimes of the devices. This led to the application of single-channel telemetry capsules for the detection of disease and abnormalities in the GI tract where restricted area prevented the use of traditional endoscopy.They were later modified as they had the disadvantage of using laboratory type sensors such as the glass pH electrodes, resistance thermometers, etc. They were also of very large size. The later modification is similar to the above instrument but is smaller in size due to the application of existing semiconductor fabrication technologies. These technologies led to the formation of “MICROELECTRONIC PILL”. Microelectronic pill is basically a multichannel sensor used for remote biomedical measurements using micro technology. This is used for the real-time measurement parameters such as temperature, pH, conductivity and dissolved oxygen. The sensors are fabricated using electron beam and photolithographic pattern integration and were controlled by an application specific integrated circuit (ASIC).